R/generics.R
ThinDataToSummarizedExperiment.Rd
This only keeps the mat
, design_obs
, designmat
,
and coefmat
elements of the ThinData object.
ThinDataToSummarizedExperiment(obj)
A ThinData S3 object. This is generally output by either
thin_diff
, thin_2group
,
thin_lib
, thin_gene
, or
thin_all
.
A SummarizedExperiment
S4
object. This is often used in Bioconductor when performing
differential expression analysis.
# \donttest{
## Generate simulated data and modify using thin_diff().
## In practice, you would use real data, not simulated.
set.seed(1)
n <- 10
p <- 1000
Z <- matrix(abs(rnorm(n, sd = 4)))
alpha <- matrix(abs(rnorm(p, sd = 1)))
mat <- round(2^(alpha %*% t(Z) + abs(matrix(rnorm(n * p, sd = 5),
nrow = p,
ncol = n))))
design_perm <- cbind(rep(c(0, 1), length.out = n), runif(n))
coef_perm <- matrix(rnorm(p * ncol(design_perm), sd = 6), nrow = p)
design_obs <- matrix(rnorm(n), ncol = 1)
target_cor <- matrix(c(0.9, 0))
thout <- thin_diff(mat = mat,
design_perm = design_perm,
coef_perm = coef_perm,
target_cor = target_cor,
design_obs = design_obs,
permute_method = "hungarian")
## Convert ThinData object to SummarizedExperiment object.
seobj <- ThinDataToSummarizedExperiment(thout)
class(seobj)
#> [1] "SummarizedExperiment"
#> attr(,"package")
#> [1] "SummarizedExperiment"
## The "O1" variable in the colData corresponds to design_obs.
## The "P1" and "P2" variables in colData correspond to design_perm.
seobj
#> class: SummarizedExperiment
#> dim: 1000 10
#> metadata(0):
#> assays(1): ''
#> rownames(1000): gene1 gene2 ... gene999 gene1000
#> rowData names(2): true_P1 true_P2
#> colnames(10): sample1 sample2 ... sample9 sample10
#> colData names(3): O1 P1 P2
# }