All functions

ThinDataToDESeqDataSet()

Converts a ThinData S3 object into a DESeqDataSet S4 object.

ThinDataToSummarizedExperiment()

Converts a ThinData S3 object into a SummarizedExperiment S4 object.

corassign()

Group assignment that is correlated with latent factors.

effective_cor()

Estimates the effective correlation.

est_sv()

Estimate the surrogate variables.

fix_cor()

Fixes an invalid target correlation.

permute_design()

Permute the design matrix so that it is approximately correlated with the surrogate variables.

poisthin()

Apply Poisson thinning to a matrix of count data.

select_counts()

Subsample the rows and columns of a count matrix.

seqgendiff-package

seqgendiff: RNA-Seq Generation/Modification for Simulation

summary(<ThinData>)

Provide summary output of a ThinData S3 object.

thin_2group()

Binomial thinning in the two-group model.

thin_all()

Binomial thinning for altering read-depth.

thin_base()

Base binomial thinning function.

thin_diff()

Binomial thinning for differential expression analysis.

thin_gene()

Binomial thinning for altering total gene expression levels

thin_lib()

Binomial thinning for altering library size.

uncorassign()

Group assignment independent of anything.