All functions |
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Converts a ThinData S3 object into a DESeqDataSet S4 object. |
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Converts a ThinData S3 object into a SummarizedExperiment S4 object. |
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Group assignment that is correlated with latent factors. |
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Estimates the effective correlation. |
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Estimate the surrogate variables. |
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Fixes an invalid target correlation. |
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Permute the design matrix so that it is approximately correlated with the surrogate variables. |
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Apply Poisson thinning to a matrix of count data. |
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Subsample the rows and columns of a count matrix. |
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seqgendiff: RNA-Seq Generation/Modification for Simulation |
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Provide summary output of a ThinData S3 object. |
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Binomial thinning in the two-group model. |
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Binomial thinning for altering read-depth. |
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Base binomial thinning function. |
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Binomial thinning for differential expression analysis. |
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Binomial thinning for altering total gene expression levels |
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Binomial thinning for altering library size. |
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Group assignment independent of anything. |